This library has substantial advantages over many similar resources including full sequence verification and knockdown validation.
The shRNA constructs have been designed and cloned into a retroviral vector and can easily be utilised for gene silencing experiments. Multiple shRNA expression vectors represent many of the genes, each with at least one shRNA construct covering a unique region of the target gene. Researchers can study the function of specific genes and also search the human genome for novel therapeutic targets for many diseases.
To search for knockdown shRNA candidates for your gene of interest, please use our GenomeCUBE® search engine below
This library is based on the production of a shRNA expressed from a vector harbouring the RNA polymerase III-driven promoter for H1 RNA, the RNA component of human RNase P. The shRNA consist of a target transcript-specific 19-base double stranded stem, connected by a 9-base loop sequence.
Each clone has the following:
We offer the complete clone set of 36 384-well microtitre plate or individual clones, for research purposes only. We can also make subsets of your chosen clones from the collection.
Please contact us to discuss your requirements.
What do do with your clones when you receive them.