Human miRNA Library (miR-Lib)
Small, endogenous (miRNAs) regulate gene expression by
mechanisms conserved across many multicelluar organisms. Recent
studies have suggested that miRNAs have a role in cellular
differentiation, tissue specification, apoptosis and the
development of various human cancers. Uncovering the functions of
the growing list of miRNAs presents a challenge to developmental
biologists.
Source BioScience LifeSciences offers the complete annotated
human miRNA library (miR-Lib). Each fragment is cloned into a
retroviral expression vector and is placed under the control of a
CMV promoter. The library was constructed using the Rfam release 6
annotated database. Each construct has been tested for its ability
to express in human cells.
For more detailed annotation, we advise that you access the
Wellcome Trust Sanger Institute microRNA website
at: http://microrna.sanger.ac.uk/
Source BioScience LifeSciences offers the complete clone set of
1 384-well microtitre plate or individual clones, for research
purposes only. We can also make subsets of your chosen clones from
the collection. Please contact us
to discuss your requirements.