Next Generation Sequencing with the HiSeq 2000 system
As a leading provider of genomic research services in Europe,
Source BioScience LifeSciences is pleased to offer Next Generation
sequencing using the HiSeq 2000™. With one HiSeq 2000™ and two
cBot cluster generation systems, we offer an experienced service
with fast turnaround time, competitive quotes and provide
researchers access to all recently launched applications.
Sequencing Technology
The Illumina sequencing system is a groundbreaking platform
for genetic analysis and functional genomics. It dramatically
improves speed and reduces costs, transforming the way many
experiments are devised and carried out. The HiSeq
2000™ leverage on the proprietary reversible terminators
and Clonal Single Molecule Array technology. The HiSeq
2000™ delivers up to two billion reads per run, generating the
industry's highest sequencing output and fastest data generation
rate.
Services Available
- Genome
Sequencing
- Single and paired-end reads allow the discovery and
confirmation of mutations, chromosomal rearrangements, de novo
sequencing and assembly
- Transcriptome
Sequencing
- Generates genome-wide expression profiles through sequencing
and not hybridization
- RNA sequencing (RNA seq), small RNA sequencing, DEEP CAGE
analysis.
- Bioinformatics
solutions
- Our Bioinformatics scientists provide a complete analysis
package that can be customised to your specific research needs
- Sample indexing
- DNA samples are tagged with a unique identifier during sample
preparation and up to 12 samples can be pooled into a single lane
to be sequenced together. This can save time and can be a cost
effective solution for sequencing
- Targeted sequencing
- Specific targeted genomic regions (either contiguous or
dispersed) are enriched for subsequent deep sequencing. The ability
to analyse only targeted regions rather than the entire complex
genome allows for effective and systematic in-depth study of
genetic variation, enabling researchers to work with larger number
of samples. We are pleased to offer target-specific sequence
selection through Agilent SureSelect™.
- Paired end sequencing
- Allows selection of a length of insert and sequencing both ends
of the insert, allowing for a highly precise alignment of
reads

Quality Assurance
We are a CSPro certified provider of Illumina sequencing. Our
laboratory is also GLP, GCP and CPA accredited.