ChIP sequencing

 

Chromatin Immunoprecipiation (ChIP) is a powerful tool in the study of interactions between proteins and DNA. ChIP-Seq combines ChIP with Genome Analyzer Sequencing technology to identify and quantify in vivo protein-DNA interactions on a genome-wide scale. Sequencing ChIP-enriched DNA fragments enables identification of binding sites of DNA-binding proteins to precisely and cost effectively map all binding sites for a protein of interest to any sequenced genome. It is widely used for proteins such as histones and transcription factors.

 

Bioinformatics Solutions

Chipdata

 

Standard

  • Raw data in fastq format
  • Manually report with run QC metrics

 

Advanced

  • Aligned reads
  • Visualisation
  • ChIP-seq analysis to determine genomic regions and peaks
  • Annotation of ChIP-seq regions and Peaks
  • Sequence motif analysis
  • Functional analyses of ChIP-seq target genes

 

Bioinformatics Support