Genome de novo Sequencing & Re-sequencing
Single and paired-end reads allow the discovery and confirmation
of mutations, chromosomal rearrangements and de novo
sequencing and assembly. The Illumina Genome Analyzer is currently
the most productive and economical tool whether you are sequencing
an entire genome or a large candidate region. The powerful
combination of a wide range of read lengths and paired-end reads of
various insert lengths enables the broadest range of genomic
applications such as:
- De novo sequencing
- Re-sequencing for SNP discovery
- Identification of copy number variations and chromosomal
Some of the popular areas in which researchers are taking
advantage of this powerful technology are:
- Human and Mammalian Genetics: Detection of
known and novel mutations in specific regions of interest using
targeted re-sequencing
- Microbial sequencing: de novo and
re-sequencing of multiple strains to look for phenotype specific
mutations
- Agrigenomics: de novo and
re-sequencing of species of commercial and research interest
- Pathogen Detection in a Host System: Detection
and characterisation of foreign DNA in infected samples from plant
or animals.
Bioinformatics Solutions
Standard
- Raw data in fastq format
- Manually report with run QC metrics
Advanced
- Visualisation
- Alignment and coverage table
- Mutation detection
- Novel mutation discovery
- Annotation of sequence polymorphism
- Functional analysis of target genes
Bioinformatics Support