Mycoplasma Detection and Eradication
Mycoplasma contamination remains a
significant problem in the culture of mammalian cells. In
contrast to other microbial contaminants, mycoplasmas do not cause
consistent perceptible changes to the cells, but they can have
disastrous effects by altering their parameters.
Source BioScience LifeSciences bring you the innovative
mycoplasma detection and eradication range from InvivoGen
Plasmocin
Plasmocin contains two bactericidal components
strongly active against mycoplasma and related cell wall-less
bacteria. It can be used to both treat
and prevent mycoplasma contamination in cell
cultures.
Further
information
Plasmotest
Plasmotest from is a rapid and simple cell
based assay for detecting mycoplasma in cell culture. It is a
cell-based colorimetric assay that exploits the ability of
Toll-like receptor 2 to recognize mycoplasmas and to induce a
signaling cascade leading to the activation of NF-kappaB and other
transcription factors. In the presence of mycoplasmas, TLR2
expressed on the surface of HEK-Blue-2 cells activates these
transcription factors which in turn induce the secretion of sAP
(secreted alkaline phosphatase), a reporter protein easily
detectable by the purple/blue coloration of the HEK-Blue Detection
medium.
Further
information
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